ERA-PG Project:
Acronym: BARCODE
Funding: 1.7 million Euros
Goals:
To integrate state of the art genomics technologies with advanced
biological resources systematically generated over the last 30 years.
This project represents a collision between historical mutation-genetics
research and advanced genomics technology. Within three clearly
defined objectives we aim to:
- Genetically map 480 morphological mutant loci onto the barley genome
(at low to medium resolution) combining use of a high throughput
gene-based SNP genotyping platform with an unique series of available
nearly isogenic mutant lines (the Bowman Series).
- Develop approximately 400Mbp of barley BAC-end sequence data linked
directly to a High Information Content Fingerprint (HICF) BAC contig-based
physical map.
- Identify, isolate and validate at least three morphologically and /
or developmentally important barley genes that are perturbed in specific
mutant lines.
The project will build upon ongoing research programs in the partner
organizations, benefiting from existing in-house and international
informatics resources for storage, analysis and graphical display of
genotypic and sequence data.
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